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Somatostatin, which is made in the pituitary and other glands, blocks growth hormone (somatotropin) production by adenomas and returns insulin-like growth factor-1 (IGF-1) to normal levels in about two thirds of patients.
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Among the 31 case patients, 6 were currently exposed to pergolide, 6 were currently exposed to cabergoline, and 19 had no current or recent exposure to a dopamine agonist ().
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The purpose of this letter is to urge an immediate external investigation in order to stop unequivocally dangerous procedures at the Bethesda National Naval Medical Center (NNMC), now the Walter Reed National Military Medical Center, and possible problems at the National Institutes of Health (NIH) that have resulted in the recent deaths (in August and September) of two NIH patients because they were given transfusions of blood platelets (blood cells that help to stop bleeding) previously determined and labeled by the NNMC blood bank to be infected with bacteria.
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In women, prolactin regulates periods and helps the breasts grow and produce milk.
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Similarly, in another study, the rate of prolactin normalization was approximately 75% in males with macroprolactinoma following 24 months of cabergoline treatment ().
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